Antiatherosclerotic agents. A structurally novel bivalent inhibitor of acylCoA:cholesterol O-acyltransferase with systemic activity

J Med Chem. 1990 Oct;33(10):2685-7. doi: 10.1021/jm00172a001.

Authors

R B Gammill¹, F P Bell, L T Bell, S N Bisaha, G J Wilson

Affiliation

¹ Upjohn Laboratories, Upjohn Company, Kalamazoo, Michigan 49001.

PMID: 2213821
DOI: 10.1021/jm00172a001

No abstract available

MeSH terms

Animals
Aorta / enzymology
Arteriosclerosis / prevention & control*
Cholesterol / blood
Chromones / chemical synthesis
Chromones / pharmacology*
Liver / enzymology
Rabbits
Rats
Sterol O-Acyltransferase / antagonists & inhibitors*
Structure-Activity Relationship

Substances

Chromones
Cholesterol
Sterol O-Acyltransferase